{"id":153862,"date":"2024-05-02T13:47:30","date_gmt":"2024-05-02T17:47:30","guid":{"rendered":"https:\/\/www.hajim.rochester.edu\/senior-design-day\/?p=153862"},"modified":"2025-05-02T14:47:42","modified_gmt":"2025-05-02T18:47:42","slug":"danimer-scientific","status":"publish","type":"post","link":"https:\/\/www.hajim.rochester.edu\/senior-design-day\/danimer-scientific\/","title":{"rendered":"Danimer Scientific"},"content":{"rendered":"\r\n<h2 class=\"wp-block-heading\">Authors<\/h2>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li>Anika Callanan<\/li>\r\n\r\n\r\n\r\n<li>Miraz A. Sadi<\/li>\r\n\r\n\r\n\r\n<li>Quinn Taylor<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\">Mentors<\/h2>\r\n\r\n\r\n\r\n<p>Mitch Anthamatten and Melodie Lawton ( Department of Chemical Engineering)<\/p>\r\n\r\n\r\n\r\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\r\n\r\n\r\n\r\n<p>The crystallization speed of a polymer can be a limiting step in the production of products. The sponsor of the project, Danimer Scientific, posed the problem of slow crystallization, and the goal of increasing the crystallization temperature (Tc) of the biodegradable polymer, poly(3-hydroxypropionic acid) (P3HP). A bio-based nucleator was used to increase the polymer\u2019s Tc. A DSC screen was conducted using several bio-based additives where orotic acid (OA) was the most promising candidate. To study the scaled-up production of the polymer, a temperature-controlled mold was designed to study isothermal crystallization during the process.<\/p>\r\n<h2 class=\"wp-block-heading\">Introduction<\/h2>\r\n<p><strong>Background:<\/strong><br \/>The production of non-biodegradable plastic is projected to triple over the next decades, potentially leading to a quadrupling in plastic pollution in oceans (The Guardian, 2016).\u00a0<\/p>\r\n<p>P3HP is an emerging biodegradable polymer produced by Danimer Scientific.\u00a0<\/p>\r\n<p>The polymer has a long crystallization time, prompting the exploration of bio-based additives to accelerate crystallization and reduce processing time.<\/p>\r\n<p>The Tc of a polymer is the temperature at which the polymer organizes itself into a\u00a0crystalline structure.\u00a0<\/p>\r\n<p>Nucleators decrease the energy barrier for crystallization, increasing the temperature that crystallization occurs because less energy has to be put in to overcome the barrier [1].<\/p>\r\n<p>Nucleators increase the number of crystallization sites, impacting crystal size and thus, mechanical properties<\/p>\r\n<p>Certain biobased additives increase the crystallization speed of similar polymers such as polyhydroxyalkanoate [2] and poly(L-lactide) [3].<\/p>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-162272\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/04\/Screenshot-2024-04-28-at-4.44.24\u202fPM.png\" alt=\"\" width=\"218\" height=\"124\" \/><\/p>\r\n<p><strong>Objective:<\/strong><\/p>\r\n<ul>\r\n<li>To utilize a bio-based nucleator to increase the Tc of P3HP, enhancing process efficiency<\/li>\r\n<li>To scale up the process of crystallizing the polymer by creating a tool to control isothermal crystallization for an industrial process<\/li>\r\n<\/ul>\r\n<p>&nbsp;<\/p>\r\n<h2 class=\"wp-block-heading\">Methodology<\/h2>\r\n<p><strong>Full Process<\/strong><\/p>\r\n<figure id=\"attachment_170312\" aria-describedby=\"caption-attachment-170312\" style=\"width: 428px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170312\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.17.37-PM-300x188.png\" alt=\"\" width=\"428\" height=\"268\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.17.37-PM-300x188.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.17.37-PM-1024x644.png 1024w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.17.37-PM-768x482.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.17.37-PM.png 1026w\" sizes=\"auto, (max-width: 428px) 100vw, 428px\" \/><figcaption id=\"caption-attachment-170312\" class=\"wp-caption-text\">Figure 1: Process Flow Diagram<\/figcaption><\/figure>\r\n<ol style=\"font-weight: 400;\">\r\n<li data-charcodes=\"65533,0,46\" data-buautonum=\"8\" data-margin=\"810\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Additive selection<\/span>\u200b<\/li>\r\n<li data-charcodes=\"65533,0,46\" data-buautonum=\"8\" data-margin=\"810\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Making pellets (done at\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">Danimer Scientific)<\/span>\u200b<\/li>\r\n<li data-charcodes=\"65533,0,46\" data-buautonum=\"8\" data-margin=\"810\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Injection into temperature-<\/span><span data-usefontface=\"true\" data-contrast=\"none\">controlled mold<\/span>\u200b<\/li>\r\n<li data-charcodes=\"65533,0,46\" data-buautonum=\"8\" data-margin=\"810\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Wait 72 hours after\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">production<\/span>\u200b<\/li>\r\n<li data-charcodes=\"65533,0,46\" data-buautonum=\"8\" data-margin=\"810\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Scaled-up property\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">testing\u00a0<\/span><\/li>\r\n<\/ol>\r\n<p>&nbsp;<\/p>\r\n<p>&nbsp;<\/p>\r\n<p><strong>Characterization of Nucleators<\/strong><\/p>\r\n<figure id=\"attachment_170522\" aria-describedby=\"caption-attachment-170522\" style=\"width: 428px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170522\" style=\"font-size: 1.25rem;\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-scan-300x202.png\" alt=\"\" width=\"428\" height=\"288\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-scan-300x202.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-scan-1024x690.png 1024w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-scan-768x517.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-scan.png 1048w\" sizes=\"auto, (max-width: 428px) 100vw, 428px\" \/><figcaption id=\"caption-attachment-170522\" class=\"wp-caption-text\">Figure 2: DSC exotherm of neat P3HP and 1% OA<\/figcaption><\/figure>\r\n<p><span style=\"font-size: 1.25rem;\" data-usefontface=\"true\" data-contrast=\"none\">Differential Scanning Calorimetry (DSC) and Polarized <\/span><span style=\"font-size: 1.25rem;\" data-usefontface=\"true\" data-contrast=\"none\">Optical Microscope (POM) were used to select an\u00a0<\/span><span style=\"font-size: 1.25rem;\" data-usefontface=\"true\" data-contrast=\"none\">additive and evaluate its effect on P3HP on a bench\u00a0<\/span><span style=\"font-size: 1.25rem;\" data-usefontface=\"true\" data-contrast=\"none\">scale (powder).\u00a0<\/span><span style=\"font-size: 1.25rem;\">\u200b<\/span><\/p>\r\n<ul style=\"font-weight: 400;\">\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">DSC produced an exotherm showing the Tc<\/span>\u200b<\/li>\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Gel Permeation Chromatography (GPC) evaluated\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">the molar mass degradation\u00a0after DSC<\/span>\u200b<\/li>\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">POM qualitatively analyzed crystal structures<\/span><\/li>\r\n<\/ul>\r\n<p data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559683&quot;:0,&quot;335559685&quot;:0,&quot;335559731&quot;:0,&quot;335559737&quot;:0,&quot;335562764&quot;:2,&quot;335562765&quot;:1,&quot;335562766&quot;:4,&quot;335562767&quot;:0,&quot;335562768&quot;:4,&quot;335562769&quot;:0}\"><b><span data-usefontface=\"true\" data-contrast=\"none\">Scale Up:<\/span><\/b>\u200b<\/p>\r\n<p data-ccp-props=\"{&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559683&quot;:0,&quot;335559685&quot;:0,&quot;335559731&quot;:0,&quot;335559737&quot;:0,&quot;335562764&quot;:2,&quot;335562765&quot;:1,&quot;335562766&quot;:4,&quot;335562767&quot;:0,&quot;335562768&quot;:4,&quot;335562769&quot;:0}\"><span data-usefontface=\"true\" data-contrast=\"none\">The process was scaled up using a temperature-<\/span><span data-usefontface=\"true\" data-contrast=\"none\">controlled mold for an injection\u00a0molder\u00a0which\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">produced dog bones for mechanical property testing.\u00a0<\/span>\u200b<\/p>\r\n<ul style=\"font-weight: 400;\">\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Morgan Press\u00a0melted pellets and injects into mold\u00a0<\/span>\u200b<\/li>\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Cooling channels machined into aluminum block\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">and top of mold<\/span>\u200b<\/li>\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"6\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">Tensile testing using Instron to obtain Young&#8217;s\u00a0<\/span><span data-usefontface=\"true\" data-contrast=\"none\">Modulus (YM)\u00a0<\/span>\u200b<\/li>\r\n<li data-charcodes=\"8226\" data-font=\"Arial,Sans-Serif\" data-buautonum=\"8\" data-margin=\"540\" data-aria-posinset=\"7\" data-aria-level=\"1\"><span data-usefontface=\"true\" data-contrast=\"none\">DSC run on dog bones show scaled-up Tc\u00a0changes<\/span><\/li>\r\n<\/ul>\r\n<figure id=\"attachment_170352\" aria-describedby=\"caption-attachment-170352\" style=\"width: 451px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170352\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.27.17-PM-300x234.png\" alt=\"\" width=\"451\" height=\"352\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.27.17-PM-300x234.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.27.17-PM-1024x800.png 1024w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.27.17-PM-768x600.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.27.17-PM.png 1298w\" sizes=\"auto, (max-width: 451px) 100vw, 451px\" \/><figcaption id=\"caption-attachment-170352\" class=\"wp-caption-text\">Figure 3: Experimental setup A) Morgan Press connecting\u00a0to chiller B) temperature-controlled mold\u00a0C) original\u00a0and elongated dog bones<\/figcaption><\/figure>\r\n<p><strong>Design of Experiments (DOE)<\/strong><\/p>\r\n<table width=\"815\">\r\n<tbody>\r\n<tr>\r\n<td width=\"242\">\r\n<p>Factors<\/p>\r\n<\/td>\r\n<td width=\"371\">\r\n<p>Levels<\/p>\r\n<\/td>\r\n<td width=\"202\">\r\n<p>Responses<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td width=\"242\">\r\n<p>Mold Temperature<\/p>\r\n<\/td>\r\n<td width=\"371\">\r\n<p>20\u02daC, 25\u02daC, 30\u02daC (Neat)<\/p>\r\n<p>35\u02daC, 40\u02daC, 45\u02daC (1% OA)<\/p>\r\n<\/td>\r\n<td rowspan=\"2\" width=\"202\">\r\n<p>Young\u2019s Modulus,\u00a0<\/p>\r\n<p>Tc<\/p>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td width=\"242\">\r\n<p>Additive Loading<\/p>\r\n<\/td>\r\n<td width=\"371\">\r\n<p>0% OA (neat), 1% OA<\/p>\r\n<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<h2 class=\"wp-block-heading\">Results<\/h2>\r\n<p><strong>Characterization<\/strong><\/p>\r\n<p>OA was found to be the most effective nucleator for P3HP.<\/p>\r\n<ul>\r\n<li>OA increased Tc more than the other additives<\/li>\r\n<li>GPC results showed OA as the only nucleator adding thermal stability<\/li>\r\n<\/ul>\r\n<figure id=\"attachment_170362\" aria-describedby=\"caption-attachment-170362\" style=\"width: 242px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170362\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-characterization-275x300.jpg\" alt=\"\" width=\"242\" height=\"264\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-characterization-275x300.jpg 275w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-characterization-940x1024.jpg 940w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-characterization-768x837.jpg 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/DSC-characterization.jpg 1246w\" sizes=\"auto, (max-width: 242px) 100vw, 242px\" \/><figcaption id=\"caption-attachment-170362\" class=\"wp-caption-text\">Figure 4: Screening\u00a0Results for 5% by mass nucleator and neat polymer<\/figcaption><\/figure>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170382 alignnone\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.36.34-PM-300x173.png\" alt=\"\" width=\"346\" height=\"200\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.36.34-PM-300x173.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.36.34-PM.png 700w\" sizes=\"auto, (max-width: 346px) 100vw, 346px\" \/><\/p>\r\n<p>&nbsp;<\/p>\r\n<p>&nbsp;<\/p>\r\n<p><span style=\"font-size: 1.25rem;\">POM images showed OA as an effective nucleator.\u00a0<\/span><\/p>\r\n<ul>\r\n<li>Neat P3HP and 1% OA were heated to 140\u00b0C, and cooled to their respective Tc\u00a0<\/li>\r\n<li>OA allowed\u00a0crystals to form more homogenously than\u00a0when the polymer lacked a nucleator<\/li>\r\n<li>Crystal sizes are smaller with 1%\u00a0OA,\u00a0indicating\u00a0an increased number of nucleation\u00a0sites, preventing crystals from reaching larger sizes\u00a0<\/li>\r\n<\/ul>\r\n<figure id=\"attachment_170402\" aria-describedby=\"caption-attachment-170402\" style=\"width: 484px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170402\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.38.56-PM-300x213.png\" alt=\"\" width=\"484\" height=\"343\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.38.56-PM-300x213.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.38.56-PM-1024x726.png 1024w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.38.56-PM-768x544.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.38.56-PM.png 1250w\" sizes=\"auto, (max-width: 484px) 100vw, 484px\" \/><figcaption id=\"caption-attachment-170402\" class=\"wp-caption-text\">Figure 5: POM images A)\u00a0Neat P3HP melt at 140\u00b0C. B) Neat P3HP at its\u00a0Tc\u00a0of 25\u00b0C.\u00a0C) 1% OA melt at 140\u00b0C. D) 1% OA at its Tc\u00a0of 40\u00b0C.<\/figcaption><\/figure>\r\n<p><strong>Scale Up<\/strong><\/p>\r\n<figure id=\"attachment_170482\" aria-describedby=\"caption-attachment-170482\" style=\"width: 397px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170482\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Main-Effects-Plot-300x194.png\" alt=\"\" width=\"397\" height=\"257\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Main-Effects-Plot-300x194.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Main-Effects-Plot-768x497.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Main-Effects-Plot.png 974w\" sizes=\"auto, (max-width: 397px) 100vw, 397px\" \/><figcaption id=\"caption-attachment-170482\" class=\"wp-caption-text\">Figure 6: YM main effects plot<\/figcaption><\/figure>\r\n<p>Tensile testing showed:<\/p>\r\n<ul>\r\n<li>Increased mold temperature yielded a higher YM product<\/li>\r\n<li>Additive loading had little effect on YM<\/li>\r\n<\/ul>\r\n<p>&nbsp;<\/p>\r\n<figure id=\"attachment_170492\" aria-describedby=\"caption-attachment-170492\" style=\"width: 495px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-170492\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Youngs-Modulus-300x181.png\" alt=\"\" width=\"495\" height=\"299\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Youngs-Modulus-300x181.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Youngs-Modulus-768x463.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Youngs-Modulus.png 956w\" sizes=\"auto, (max-width: 495px) 100vw, 495px\" \/><figcaption id=\"caption-attachment-170492\" class=\"wp-caption-text\">Figure 7: YM comparison after scale up<\/figcaption><\/figure>\r\n<p><span style=\"font-size: 1.25rem;\">Neat and 1% OA show different YM trends:<\/span><\/p>\r\n<ul>\r\n<li>YM for 1% OA increases with increased mold temperature<\/li>\r\n<li>Neat remains inconclusive<\/li>\r\n<li>Limited material prevented further analysis of neat P3HP<\/li>\r\n<li>Air bubble in a neat dog bone resulted in lower YM<\/li>\r\n<li>1% OA showed increasing YM with increasing mold temperature<\/li>\r\n<\/ul>\r\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-170502 alignright\" src=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.49.17-PM-300x90.png\" alt=\"\" width=\"300\" height=\"90\" srcset=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.49.17-PM-300x90.png 300w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.49.17-PM-768x230.png 768w, https:\/\/www.hajim.rochester.edu\/senior-design-day\/wp-content\/uploads\/2024\/05\/Screen-Shot-2024-05-01-at-4.49.17-PM.png 814w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>The scaled-up\u00a01% OA polymer product also showed\u00a0an increase in Tc when compared to the neat dog\u00a0bones.\u200b<\/p>\r\n<ul>\r\n<li>Larger increase between neat and OA Tc for scaled-up process compared to bench scale<\/li>\r\n<li>Both show statically significant change in Tc<\/li>\r\n<\/ul>\r\n<h2 class=\"wp-block-heading\">Conclusions and Future Work<\/h2>\r\n<p><b>Conclusions:<\/b><\/p>\r\n<ul>\r\n<li>The Tc of P3HP was increased by 10\u00b0C when scaled up<\/li>\r\n<li>A 10\u00b0C increase in the mold temperature increased the YM of the scaled-up 1% OA product by roughly 20%.\u00a0<\/li>\r\n<li>The development of a scaled-up injection molding process with controlled crystallization using a custom cooling mold<\/li>\r\n<\/ul>\r\n<p><b>Future Work:<\/b><\/p>\r\n<ul>\r\n<li>Compound mixing to evaluate different OA loadings to determine optimal percent to maximize Tc increase<\/li>\r\n<li>Optimizing Morgan Press parameters for scale up process (injection pressure,\u00a0coolant temperature,\u00a0injection speed) to determine which conditions eliminate air bubbles<\/li>\r\n<li>Use a larger sample size to help support the above preliminary results<\/li>\r\n<\/ul>\r\n<h2 class=\"wp-block-heading\">Acknowledgments\u00a0<\/h2>\r\n<p>Team Parkour! would like to thank Prof. Lawton and Prof. Anthamatten for advising us this semester. We would like to thank Clair Cunningham, Jeff Lefler, Bill Mildenberger, and Prof. Kelley for assisting in the design and build. Additionally, we want to express our thanks to Kimberly Clem and Ben Carlson for helping us through this project. Finally, we would like to thank Dr. Chris DeRosa and Danimer Scientific for sponsoring this project and the Department of Chemical Engineering for their support.<\/p>\r\n<h2 class=\"wp-block-heading\">References<\/h2>\r\n<p>1.Zhang, X., Meng, L., Li, G., Liang, N., Zhang, J., Zhu, Z. and Wang, R. (2016), Effect of nucleating agents on the\u00a0crystallization behavior and heat resistance of poly(l-lactide).\u00a0<i>J. Appl.\u00a0<\/i><i>Polym<\/i><i>. Sci.<\/i>, 133, 42999.<\/p>\r\n<p>2.Bledsoe, J., Crane, G., and Locklin, J. Beyond Lattice Matching: The Role of Hydrogen Bonding in Epitaxial\u00a0Nucleation of Poly(hydroxyalkanoates) by\u00a0Methylxathines. Applied Polymer Materials. 2023.\u00a0<\/p>\r\n<p>3.Qiu, Zhaobin and Li Zhisheng. Effect of Orotic Acid on the Crystallization Kinetics and Morphology of Biodegradable Poly(L-lactide) as an Efficient Nucleating Agent. I&amp;EC Research. 2011.<\/p>\r\n<p>4.DeRosa, Chris. \u201cNucleation of Poly(Propiolactone).\u201d Danimer Scientific 2023.\u00a0<\/p>\r\n<p>&nbsp;<\/p>\r\n","protected":false},"excerpt":{"rendered":"<p>Authors Mentors Mitch Anthamatten and Melodie Lawton ( Department of Chemical Engineering) Abstract The crystallization speed of a polymer can be a limiting step in the production of products. The&hellip;<\/p>\n","protected":false},"author":6242,"featured_media":183082,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[4442,76],"tags":[],"coauthors":[8612],"class_list":["post-153862","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-archive","category-che-archive"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Danimer Scientific - Senior Design Day<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hajim.rochester.edu\/senior-design-day\/danimer-scientific\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Danimer Scientific - Senior Design Day\" \/>\n<meta property=\"og:description\" content=\"Authors Mentors Mitch Anthamatten and Melodie Lawton ( Department of Chemical Engineering) Abstract The crystallization speed of a polymer can be a limiting step in the production of products. 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