{"id":187782,"date":"2025-05-05T09:23:26","date_gmt":"2025-05-05T13:23:26","guid":{"rendered":"https:\/\/www.hajim.rochester.edu\/senior-design-day\/?p=187782"},"modified":"2026-05-04T10:34:08","modified_gmt":"2026-05-04T14:34:08","slug":"creating-phantom-retinas-for-fundus-imaging-zeiss","status":"publish","type":"post","link":"https:\/\/www.hajim.rochester.edu\/senior-design-day\/creating-phantom-retinas-for-fundus-imaging-zeiss\/","title":{"rendered":"Creating Phantom Retinas for Fundus Imaging – ZEISS"},"content":{"rendered":"\n

Authors<\/strong><\/p>\n\n\n\n

Riley Semler, Shuo Wang, Isaac Ondo<\/p>\n\n\n\n

Faculty Advisor<\/strong><\/p>\n\n\n\n

Mark Buckley<\/p>\n\n\n\n

Abstract<\/strong><\/p>\n\n\n\n

When training clinicians to image human eyes, it is important to have accurate models for them to practice on and to calibrate the instruments by. Our team was tasked with creating long lasting, shelf stable retina phantoms, or model retinas, which accurately match the reflection spectrum and visual details of a human retina. These models for fundus imaging are to show several key features, such as blood vessels, the optic nerve, and the retinal disease drusen, along with accurately mimicking the pigments in the eye, such as melanin. We did this by doping contact lenses with various materials and dyes and stacking them to create the layers we wanted. The camera used for measurements was the handheld Zeiss Visuscout camera. In the end, we created several phantoms which replicated different structures and colors of the parts of the retina<\/p>\n\n\n\n

Background<\/strong><\/p>\n\n\n\n

Having accurate models of the eye is important for both training doctors to use the company\u2019s products as well as calibrating the devices. The company Zeiss asked our senior design group to look at possible ways to create these models and address several limitations that models currently on the market have, namely shelf life. These cameras use fundus imaging, which is a way of imaging the retina that only takes a picture inside the eye, and doesn\u2019t see three dimensional depth of structures in the eye, like optical coherence tomography does.<\/p>\n\n\n\n

The camera we were given to test with was the Zeiss Visuscout, which is a portable handheld camera, and has similar responses to wavelengths as their other products these phantoms would be used on, like the Clarus 500.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Figure 1. Graph of absorptivity of certain key pigments[1]<\/em><\/p>\n\n\n\n

\"A<\/figure>\n\n\n\n

Figure 2. Picture of human retina with drusen obtained through fundus imaging [2]<\/em><\/p>\n\n\n\n

\"A<\/figure>\n\n\n\n

Figure 3. Picture of Visuscout camera [3]<\/em><\/p>\n\n\n\n

We wanted our phantoms to:<\/p>\n\n\n\n