The Translational Center for Barrier Microphysiological Systems (TraCe-bMPS) develops and applies chip-based models of healthy and diseased human tissue. These multicellular models enable reductionist studies of disease mechanisms and are increasingly valued in the discovery and regulatory phases of drug development. TraCe-bMPS is powered by University of Rochester technologies and through partnerships with industry and academia. Resource sharing and collaboration are a central part of the Center’s mission. So if you see an opportunity with us, please inquire.
TraCe-bMPS teams are building a variety of human tissue models on our device platforms. Notable examples include tendon fibrosis and sepsis-associated encephalopathy. Common to these efforts is the need to simulate the exchange of cells and molecules across the barriers that compartmentalize human tissue. The models provide access to reliable measurements of physiological responses that reveal human disease mechanisms and help identify new treatments.
We encourage the adoption of our tissue modeling platforms and the development of novel models featuring our core technologies. We provide support through open-access protocols, communication platforms, a training program at the University of Rochester, and external workshops. Materials and services are available through our resource core, academic laboratories, and commercial partners. To access these resources, request an affiliation with TraCe-bMPS.