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Danielle Benoit Awarded Five Year Grant From NIH

March 5, 2013

Danielle Benoit, Ph.D., assistant professor of Biomedical Engineering, has been awarded a five year grant from National Institutes of Health, specifically the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), for the project, entitled: Tissue engineering strategies to revitalize bone allografts. This project focuses on the revitalization of allografts using tissue-engineering strategies to recapitulate critical healing functions of the periosteum. Our objective is to develop periosteum mimetics composed of synthetic hydrogels (poly(ethylene glycol), PEG) for MSC transplantation to:

  • Promote cell-mediated allograft healing/integration
  • Isolate the critical factors of the periosteum in healing
  • Develop cell-free therapies that result in complete allograft healing and integration