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Parker Medical Imaging Research

OCT Elastography

Elastography is a technique that measures and maps the local elastic property of biological tissues. Aiming for detection of micron-scale inclusions, various optical elastography, especially optical coherence elastography (OCE), techniques have been investigated over the past decade. The challenges of current optical elastography methods include the decrease in elastographic resolution as compared with its parent imaging resolution, the detection sensitivity and accuracy, and the cost of the overall system. We developed 'crawling wave optical coherence elastography' (CRW-OCE), which significantly lowers the requirements on the imaging speed and opens the path to high-resolution and high-sensitivity OCE at relatively low cost. Methods of crawling wave excitation, data acquisition, and crawling wave tracking are presented.


Journal Articles


  1. Comparative study of shear wave-based elastography technques in optical coherence tomography
    F. Zvietcovich, J. P. Rolland, J. Yao, P. Meemon, and K. J. Parker
    SPIE Journal of Biomedical Optics, vol. 22, no. 3 , pp. 035010-1 -035010-17  (2017). View PDF
  2. A comparative study of shear wave speed estimation techniques in optical coherence elastography
    F. Zvietcovich, J. Yao, Y. Chu, P. Meemon, J. P. Rolland, and K. J. Parker
    Proceedings SPIE 9710 Photonics West, Optical Elastography and Tissue Biomechanics III, vol. 9710 , pp. 97100Y-1 - 97100Y-11  (2016). View Online
  3. Experimental classification of surface waves in optical coherence elastography
    F. Zvietcovich, J. Yao, J. P. Rolland, and K. J. Parker
    Proceedings SPIE 9710 Photonics West, Optical Elastography and Tissue Biomechanics III, vol. 9710 , pp. 97100Z-1 - 97100Z-9  (2016). View Online
  4. Crawling wave optical coherence elastography
    P. Meemon, J. Yao, Y. Chu, F. Zvietcovich, K. J. Parker, and J. P. Rolland
    Optics Letters, vol. 41, no. 5 , pp. 847 -850  (2016). View Online